EIF5A antibody

GeneTex

EIF5A antibody

9

WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.4 mg/ml

Unconjugated

EIF5A

eukaryotic translation initiation factor 5A

eIF-4D; EIF-5A; EIF5A1; eIF5AI; eukaryotic initiation factor 5A; eukaryotic translation initiation factor 5A-1; FABAS; rev-binding factor

Rabbit

IgG

Eukaryotic translation initiation factor 5A-1

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of TP53/p53 and TP53/p53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203