ELA-32(human) [1680205-79-1]

TargetMol Chemicals

ELA-32(human) [1680205-79-1]

999

1680205-79-1

Research Use Only

ELA-32(human)

C170H289N63O39S4

3967.8

Potent, high affinity apelin receptor agonist (IC50 = 0.27 nM; Kd = 0.51 nM). Exhibits no binding GPR15 and GPR25. Activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. Also potentiates the TGFbeta pathway, priming hESCs toward the endoderm lineage. Stimulates angiogenesis in HUVEC cells. Relaxes mouse aortic vessels. Functions as an anorexigenic hormone through activation of the AVP and CRH neurons in the PVN.

3 years

-20°C

12352200