ELA-32(human) TFA
ORB1981409
Estimated Purity98.00%
Product group Chemicals
Molecular Weight4081.84
Overview
- SupplierBiorbyt
- Product NameELA-32(human) TFA
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity98.00%
- Molecular FormulaC172H290F3N63O41S4
- Molecular Weight4081.84
- Scientific DescriptionELA-32(human) TFA is a potent apelin receptor agonist with high affinity, demonstrating an IC50 of 0.27 nM and a Kd of 0.51 nM. This compound does not bind to GPR15 or GPR25. It activates the PI3K/AKT signaling pathway, facilitating self-renewal of human embryonic stem cells (hESCs) through cell-cycle progression and protein synthesis. Additionally, ELA-32(human) TFA enhances the TGFbeta pathway, predisposing hESCs towards an endoderm lineage, and promotes angiogenesis in HUVEC cells.
- Storage Instruction-20°C
- UNSPSC12352200