ELA-32(human) TFA

TargetMol Chemicals

ELA-32(human) TFA

999

Chemical

Research Use Only

ELA-32(human) TFA

C172H290F3N63O41S4

4081.84

ELA-32(human) TFA is a potent apelin receptor agonist with high affinity, demonstrating an IC50 of 0.27 nM and a Kd of 0.51 nM. This compound does not bind to GPR15 or GPR25. It activates the PI3K/AKT signaling pathway, facilitating self-renewal of human embryonic stem cells (hESCs) through cell-cycle progression and protein synthesis. Additionally, ELA-32(human) TFA enhances the TGFbeta pathway, predisposing hESCs towards an endoderm lineage, and promotes angiogenesis in HUVEC cells.

3 years

-20°C

12352200