ELAC2 antibody

GeneTex

ELAC2 antibody

9

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:100. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

ELAC2

elaC ribonuclease Z 2

COXPD17, ELC2, HPC2, zinc phosphodiesterase ELAC protein 2, RNase Z 2, elaC homolog 2, elaC homolog protein 2, elaC-like protein 2, heredity prostate cancer protein 2, putative prostate cancer susceptibility protein HPC2/ELAC2, ribonuclease Z 2, tRNA 3 endonuclease 2, tRNase Z (long form), tRNase Z 2

Rabbit

IgG

Zinc phosphodiesterase ELAC protein 2

The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3 trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

-20°C or -80°C,2°C to 8°C

12352203