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ProductsBack/ELAC2 Polyclonal Antibody

Western blot analysis of extracts of various cell lines using ELAC2 Polyclonal Antibody at 1:1000 dilution.

Western blot analysis of extracts of various cell lines using ELAC2 Polyclonal Antibody at 1:1000 dilution.

Western blot analysis of extracts of various cell lines using ELAC2 Polyclonal Antibody at 1:1000 dilution.

ELAC2 Polyclonal Antibody

E-AB-61543

Product group Antibodies

Overview

Supplier
Elabscience
Product Name
ELAC2 Polyclonal Antibody
Delivery Days Customer
12
Certification
Research Use Only
Scientific Description
The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3 trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
UNSPSC
12352203