Western blot analysis of extracts of various cell lines using ELAC2 Polyclonal Antibody at 1:1000 dilution.
ELAC2 Polyclonal Antibody
E-AB-61543
Product group Antibodies
Overview
- SupplierElabscience
- Product NameELAC2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3 trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
- UNSPSC12352203