Elesclomol

MedChem Express

Elesclomol [488832-69-5]

10

488832-69-5

Research Use Only

99.80

C19H20N4O2S2

400.5177

Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death ( cuproptosis ). Elesclomol specifically binds ferredoxin 1 (FDX1) alpha2/alpha3 helices and beta5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research [1] [2] [3] [4] .

S=C(C1=CC=CC=C1)N(NC(CC(NN(C(C2=CC=CC=C2)=S)C)=O)=O)C

-20°C,2°C to 8°C

12352200