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ELISA Kit for Cyclophilin A (CYPA)

SEA979HU
Cloud-Clone Corp.
Product group Assays
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Overview

  • Supplier
    Cloud-Clone Corp.
  • Product Name
    ELISA Kit for Cyclophilin A (CYPA)
  • Delivery Days Customer
    12
  • Assay Detection Range
    1.25-80ng/mL
  • Assay Precision
    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Cyclophilin A (CYPA) were tested 20 times on one plate, respectively. Inter-assay Precision (Precision between assays): 3 samples with low, middle and high ...
  • Assay Sensitivity
    The minimum detectable dose of this kit is typically less than 0.49ng/mL
  • Assay Specificity
    This assay has high sensitivity and excellent specificity for detection of Cyclophilin A (CYPA). No significant cross-reactivity or interference between Cyclophilin A (CYPA) and analogues was observed.
  • Assay Test Principle
    The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Cyclophilin A (CYPA). Standards or samples are then added to the appropriate microtiter ...
  • Assay Time
    3h
  • Certification
    Research Use Only
  • UNSPSC
    41116158

References

  • Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity. Ramachandran S et al., 2018 Mar 30, Clin Sci (Lond)
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  • Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus. Ramachandran S et al., 2016 Nov 3, Cardiovasc Diabetol
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  • PPIA rs6850: A > G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease. Vinitha A et al., 2016 Jan, Mol Cell Biochem
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  • Urinary Cyclophilin A as a New Marker for Diabetic Nephropathy: A Cross-Sectional Analysis of Diabetes Mellitus. Tsai SF et al., 2015 Oct, Medicine (Baltimore)
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  • Cyclophilin A in Ruptured Intracranial Aneurysm: A Prognostic Biomarker. Kao HW et al., 2015 Sep, Medicine (Baltimore)
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  • Decrease in plasma cyclophilin A concentration at 1 month after myocardial infarction predicts better left ventricular performance and synchronicity at 6 months: a pilot study in patients with ST elevation myocardial infarction. Huang CH et al., 2015, Int J Biol Sci
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  • Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease. Ramachandran S et al., 2014 Feb 7, Cardiovasc Diabetol
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  • Cyclophilin-A: a novel biomarker for untreated male essential hypertension. Chang CS et al., 2013 Dec, Biomarkers
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  • EMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation. Seizer P et al., 2010 Mar, Atherosclerosis
    Read more

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