ELOVL6 antibody

GeneTex

ELOVL6 antibody

9

WB: 1 - 2 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Liquid

ELOVL6

ELOVL fatty acid elongase 6

3-keto acyl-CoA synthase ELOVL6; elongation of very long chain fatty acids protein 6; ELOVL FA elongase 6; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast); FACE; FAE; fatty acid elongase 2; fatty acyl-CoA elongase; hELO2; LCE; long-chain fatty-acyl elongase; very long chain 3-ketoacyl-CoA synthase 6; very long chain 3-oxoacyl-CoA synthase 6

Rabbit

IgG

Elongation of very long chain fatty acids protein 6

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203