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Eltanexor

HY-100423
MedChem Express
CAS Number1642300-52-4
DownloadMSDS
Product group Chemicals
Estimated Purity99.84
Molecular Weight428.29
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Eltanexor [1642300-52-4]
  • Delivery Days Customer
    14
  • CAS Number
    1642300-52-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.84
  • Molecular Formula
    C17H10F6N6O
  • Molecular Weight
    428.29
  • Scientific Description
    Eltanexor (KPT-8602) is a second-generation, highly specific and orally active exportin-1 (XPO1) inhibitor with potent anti-leukemic activity. Eltanexor (KPT-8602) inhibits XPO1-dependent nuclear export ( EC 50 =60.9 nM) by directly targeting XPO1. Eltanexor (KPT-8602) induces Caspase-dependent apoptosis in a panel of leukemic cell lines [1] .
  • SMILES
    FC(F)(F)C1=CC(C(F)(F)F)=CC(C2=NN(/C=C(C3=CN=CN=C3)/C(N)=O)C=N2)=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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