Eltanexor Z-isomer

MedChem Express

Eltanexor Z-isomer [1642300-78-4]

10

1642300-78-4

Research Use Only

95.98

C17H10F6N6O

428.29

Eltanexor Z-isomer (KPT-8602 Z-isomer) is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor. IC50 : In Vitro: Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC 50 s of 100 nM-50 microM, 30 microM, respectively [1] . In Vivo:

O=C(N)/C(C1=CN=CN=C1)=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2

-20°C,2°C to 8°C

12352200