EM574 [Motilide] [110480-13-2]

AdipoGen Life Sciences

EM574 [Motilide]

10

110480-13-2

Research Use Only

>95%

C39H69NO12

744

Chemical. CAS: 110480-13-2. Formula: C39H69NO12. MW: 744. Semisynthetic from erythromycin A. Shows strong gastrointestinal motor stimulating (GMS) activity. Motilin receptor agonist. Stimulates smooth muscle cell contraction. Stimulates cholinergic neurons in a non-vagal pathway. Enhances gastrointestinal contractile activity and accelerates gastric emptying. Shows orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, ghrelin receptor). - Shows strong gastrointestinal motor stimulating (GMS) activity [1, 2, 5]. Motilin receptor agonist [3, 6]. Stimulates smooth muscle cell contraction [3]. Stimulates cholinergic neurons in a non-vagal pathway [4]. Enhances gastrointestinal contractile activity and accelerates gastric emptying [7, 8]. Shows orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, ghrelin receptor) [9].

CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C(C)C)[C@@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O

-20°C,2°C to 8°C

12352200