Emapalumab [1709815-23-5]

TargetMol Chemicals

Emapalumab

9

1709815-23-5

Antibody

Research Use Only

Emapalumab

SDS-PAGE:95% SEC-HPLC:97.56%

Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-gamma and to IFN-gamma bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH).

3 years

-20°C

12352203