Embelin

MedChem Express

Embelin [550-24-3]

10

550-24-3

Research Use Only

98.75

C17H26O4

294.39

Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor ( IC 50 =4.1 microM), inhibits cell growth, induces apoptosis , and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells [1] [2] [3] .

O=C1C(O)=C(CCCCCCCCCCC)C(C(O)=C1)=O

2°C to 8°C

12352200