Western Blot Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate, Colo320 whole cell lysate, HepG2 whole cell lysate, Jurkat whole cell lysate, MCF-7 whole cell lysate, Mouse lung tissue All lanes: EMD antibody at 2microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 29 kDa Observed band size: 35 kDa

EMD Antibody

CSB-PA007633LA01HU

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman, Mouse

TargetEMD

Overview

Supplier
Cusabio
Product Name
EMD Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID2010
Target name
EMD
Target description
emerin
Target synonyms
EDMD; emerin; LEM domain containing 5; LEMD5; STA
Host
Rabbit
Isotype
IgG
Protein IDP50402
Protein Name
Emerin
Scientific Description
Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

EMD Antibody

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Overview

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