Emodin

MedChem Express

Emodin [518-82-1]

10

518-82-1

Research Use Only

99.39

C15H10O5

270.24

Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11beta-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11beta-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3].

O=C1C2=C(C=C(C)C=C2O)C(C3=CC(O)=CC(O)=C31)=O

-20°C,2°C to 8°C

12352200