The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA196695(EMP2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA196695(EMP2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
EMP2 Antibody
CSB-PA196695
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetEMP2
Overview
- SupplierCusabio
- Product NameEMP2 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2013
- Target nameEMP2
- Target descriptionepithelial membrane protein 2
- Target synonymsepithelial membrane protein 2; XMP
- HostRabbit
- IsotypeIgG
- Protein IDP54851
- Protein NameEpithelial membrane protein 2
- Scientific DescriptionEMP-2 (epithelial membrane protein 2), also known as XMP, is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203