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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using EMP2 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using EMP2 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using EMP2 Polyclonal Antibody at dilution 1:30

EMP2 Polyclonal Antibody

E-AB-16404
Elabscience
ApplicationsImmunoHistoChemistry
Product group Antibodies
TargetEMP2
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Overview

  • Supplier
    Elabscience
  • Product Name
    EMP2 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications
    ImmunoHistoChemistry
  • Applications Supplier
    ELISA IHC
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.8 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2013
  • Target name
    EMP2
  • Target description
    epithelial membrane protein 2
  • Target synonyms
    XMP, epithelial membrane protein 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP54851
  • Protein Name
    Epithelial membrane protein 2
  • Scientific Description
    EMP-2 (epithelial membrane protein 2), also known as XMP, is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116161

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