Encorafenib

MedChem Express

Encorafenib [1269440-17-6]

10

1269440-17-6

Research Use Only

99.93

C22H27ClFN7O4S

540.01

Encorafenib (LGX818) is a highly potent BRAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing BRAF V600E ( EC 50 =4 nM).

O=C(OC)N[C@@H](C)CNC1=NC=CC(C2=CN(C(C)C)N=C2C3=CC(Cl)=CC(NS(=O)(C)=O)=C3F)=N1

-20°C,2°C to 8°C

12352200