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Endogenous peroxidase blocking kit

GTX30967
GeneTex
Product group Chemicals
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Overview

  • Supplier
    GeneTex
  • Product Name
    Endogenous peroxidase blocking kit
  • Delivery Days Customer
    9
  • Application Supplier Note
    We recommend that endogenous peroxidase activity should be blocked following deparaffinization but prior to antigen retrieval.
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Scientific Description
    Endogenous peroxidase and pseudoperoxidase activity is found in many frozen, formalin-fixed paraffin-embedded tissue sections and cell smears. Peroxidase is most commonly found in red blood cells, myoglobin in muscle cells, cytochrome in granulocytes, and monocytes, liver and kidney. The presence of endogenous peroxidase activity gives false results when using peroxidase based Immunohistochemistry technique. For frozen tissue sections eg. Peripheral blood, bone marrow, fixation should be done with acetone/methanol.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12161700

References

  • Boschetti E, Malagelada C, Accarino A, et al. Enteric neuron density correlates with clinical features of severe gut dysmotility. Am J Physiol Gastrointest Liver Physiol. 2019,317(6):G793-G801. doi: 10.1152/ajpgi.00199.2019
    Read this paper
  • Wang N, Wang L, Meng X, et al. Osimertinib (AZD9291) increases radio‑sensitivity in EGFR T790M non‑small cell lung cancer. Oncol Rep. 2019,41(1):77-86. doi: 10.3892/or.2018.6803
    Read this paper
  • Fumery M, Speca S, Langlois A, et al. Peroxisome proliferator-activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut. EMBO Mol Med. 2017,9(11):1471-1481. doi: 10.15252/emmm.201707795
    Read this paper
  • Boschetti E, D'Alessandro R, Bianco F, et al. Liver as a source for thymidine phosphorylase replacement in mitochondrial neurogastrointestinal encephalomyopathy. PLoS One. 2014,9(5):e96692. doi: 10.1371/journal.pone.0096692
    Read this paper