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Endogenous peroxidase blocking kit

Research Use Only
GTX30967
GeneTex
Product group Chemicals
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Overview

  • Supplier
    GeneTex
  • Product Name
    Endogenous peroxidase blocking kit
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Scientific Description
    Endogenous peroxidase and pseudoperoxidase activity is found in many frozen, formalin-fixed paraffin-embedded tissue sections and cell smears. Peroxidase is most commonly found in red blood cells, myoglobin in muscle cells, cytochrome in granulocytes, and monocytes, liver and kidney. The presence of endogenous peroxidase activity gives false results when using peroxidase based Immunohistochemistry technique. For frozen tissue sections eg. Peripheral blood, bone marrow, fixation should be done with acetone/methanol.
  • UNSPSC
    12352200

References

  • Enteric neuron density correlates with clinical features of severe gut dysmotility. Boschetti E et al., 2019 Dec 1, Am J Physiol Gastrointest Liver Physiol
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  • Liver as a source for thymidine phosphorylase replacement in mitochondrial neurogastrointestinal encephalomyopathy. Boschetti E et al., 2014, PLoS One
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  • Osimertinib (AZD9291) increases radio-sensitivity in EGFR T790M non-small cell lung cancer. Wang N et al., 2019 Jan, Oncol Rep
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  • Peroxisome proliferator-activated receptor gamma (PPARgamma) regulates lactase expression and activity in the gut. Fumery M et al., 2017 Nov, EMBO Mol Med
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