Endogenous peroxidase blocking kit
GTX30967
Product group Chemicals
Overview
- SupplierGeneTex
- Product NameEndogenous peroxidase blocking kit
- Delivery Days Customer9
- Application Supplier NoteWe recommend that endogenous peroxidase activity should be blocked following deparaffinization but prior to antigen retrieval.
- ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry
- CertificationResearch Use Only
- Scientific DescriptionEndogenous peroxidase and pseudoperoxidase activity is found in many frozen, formalin-fixed paraffin-embedded tissue sections and cell smears. Peroxidase is most commonly found in red blood cells, myoglobin in muscle cells, cytochrome in granulocytes, and monocytes, liver and kidney. The presence of endogenous peroxidase activity gives false results when using peroxidase based Immunohistochemistry technique. For frozen tissue sections eg. Peripheral blood, bone marrow, fixation should be done with acetone/methanol.
- Storage Instruction2°C to 8°C
- UNSPSC12161700
References
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- Wang N, Wang L, Meng X, et al. Osimertinib (AZD9291) increases radio‑sensitivity in EGFR T790M non‑small cell lung cancer. Oncol Rep. 2019,41(1):77-86. doi: 10.3892/or.2018.6803Read this paper
- Fumery M, Speca S, Langlois A, et al. Peroxisome proliferator-activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut. EMBO Mol Med. 2017,9(11):1471-1481. doi: 10.15252/emmm.201707795Read this paper
- Boschetti E, D'Alessandro R, Bianco F, et al. Liver as a source for thymidine phosphorylase replacement in mitochondrial neurogastrointestinal encephalomyopathy. PLoS One. 2014,9(5):e96692. doi: 10.1371/journal.pone.0096692Read this paper