Endostatin antibody

GeneTex

Endostatin antibody

9

WB: 0.1-0.2 microg/ml. IHC-Fr: 15 microg/ml. ELISA: 0.5-1.0 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Polyclonal

Unconjugated

Col18a1

collagen, type XVIII, alpha 1

alpha-1(XVIII) collagen; collagen alpha-1(XVIII) chain; endo; endostatin; procollagen, type XVIII, alpha 1

Goat

IgG

Collagen alpha-1(XVIII) chain

Endostatin (20-22 kDa), a cleaved product of the C-terminal domain of collagen XVIII, is an endogenous angiogenesis inhibitor. It was originally found in conditioned media from a murine endothelial tumor cell line, hemangioendothelioma. Endostatin inhibits endothelial cell migration (in vivo and in vitro) and induces endothelial cell apoptosis. It inhibits tumor growth and impairs blood vessel maturation in wound healing. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes.

Mouse

-20°C or -80°C,2°C to 8°C

12352203