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ProductsBack/Endothelin 1 antibody [C1C3]

Endothelin 1 antibody [C1C3]

Research Use Only
GTX116033
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetEDN1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Endothelin 1 antibody [C1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.2 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID1906
  • Target name
    EDN1
  • Target description
    endothelin 1
  • Target synonyms
    ARCND3; endothelin-1; ET1; HDLCQ7; PPET1; preproendothelin-1; QME
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05305
  • Protein Name
    Endothelin-1
  • Scientific Description
    The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • EZH2, Endothelin-1, and CD34 as Biomarkers of Aggressive Cervical Squamous Cell Carcinoma: An Immunohistochemical Study. Fathy A et al., 2018, Turk Patoloji Derg
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  • Endothelin-1 receptor blockade as new possible therapeutic approach in multiple myeloma. Russignan A et al., 2017 Sep, Br J Haematol
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  • Endothelin-1 and ET receptors impair left ventricular function by mediated coronary arteries dysfunction in chronic intermittent hypoxia rats. Wang JW et al., 2017 Jan, Physiol Rep
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  • Evidence for proangiogenic cellular and humoral systemic response in patients with acute onset of spinal cord injury. Paczkowska E et al., 2015 Nov, J Spinal Cord Med
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  • Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway. Lu JW et al., 2014, PLoS One
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  • Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model. Lu JW et al., 2012 Jan, Carcinogenesis
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