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Endothelin 1 antibody [C1C3]

Name: Endothelin 1 antibody [C1C3]
SKU: GTX116033_G10
Availability: BackOrder

GTX116033

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetEDN1

Overview

Supplier
GeneTex
Product Name
Endothelin 1 antibody [C1C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.2 mg/ml
Conjugate
Unconjugated
Gene ID1906
Target name
EDN1
Target description
endothelin 1
Target synonyms
ARCND3, ET1, HDLCQ7, PPET1, QME, endothelin-1, preproendothelin-1
Host
Rabbit
Isotype
IgG
Protein IDP05305
Protein Name
Endothelin-1
Scientific Description
The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Fathy A, Abdelrahman AE. EZH2, Endothelin-1, and CD34 as Biomarkers of Aggressive Cervical Squamous Cell Carcinoma: An Immunohistochemical Study. Turk Patoloji Derg. 2018,34(2):150-57. doi: 10.5146/tjpath.2018.01425
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Russignan A, Spina C, Tamassia N, et al. Endothelin-1 receptor blockade as new possible therapeutic approach in multiple myeloma. Br J Haematol. 2017,178(5):781-793. doi: 10.1111/bjh.14771
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Wang JW, Li AY, Guo QH, et al. Endothelin-1 and ET receptors impair left ventricular function by mediated coronary arteries dysfunction in chronic intermittent hypoxia rats. Physiol Rep. 2017,5(1). doi: 10.14814/phy2.13050
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Paczkowska E, Rogińska D, Pius-Sadowska E, et al. Evidence for proangiogenic cellular and humoral systemic response in patients with acute onset of spinal cord injury. J Spinal Cord Med. 2015,38(6):729-44. doi: 10.1179/2045772314Y.0000000227
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Lu JW, Liao CY, Yang WY, et al. Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway. PLoS One. 2014,9(1):e85318. doi: 10.1371/journal.pone.0085318
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Lu JW, Hsia Y, Yang WY, et al. Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model. Carcinogenesis. 2012,33(1):209-19. doi: 10.1093/carcin/bgr224
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