Endothelin-1/EDN1, Human (GST)

MedChem Express

Endothelin-1/EDN1, Human (GST)

10

Research Use Only

95%

EDN1

endothelin 1

ARCND3, ET1, HDLCQ7, PPET1, QME, endothelin-1, preproendothelin-1

Endothelin-1

Endothelin-1/EDN1, an endothelium-derived vasoconstrictor peptide, acts as a likely ligand for G-protein coupled receptors EDNRA and EDNRB. Its binding initiates a signaling cascade in glomerular mesangial cells involving PTK2B, BCAR1, BCAR3, and GTPases RAP1 and RHOA. Furthermore, Endothelin-1/EDN1 shows binding affinity for the DEAR/FBXW7-AS1 receptor, underscoring its involvement in diverse cellular signaling and vascular regulation. Endothelin-1/EDN1 Protein, Human (GST) is the recombinant human-derived Endothelin-1/EDN1 protein, expressed by E. coli , with N-GST labeled tag.

-20°C

41116100