Bio-Connect

Engasertib [1313439-71-2]

HY-151504
MedChem Express
CAS Number1313439-71-2
Product group Chemicals
Estimated Purity99.65
Molecular Weight415.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Engasertib [1313439-71-2]
  • Delivery Days Customer
    10
  • CAS Number
    1313439-71-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.65
  • Molecular Formula
    C25H25N3O3
  • Molecular Weight
    415.48
  • Scientific Description
    Engasertib is an orally active highly specific AKT inhibitor with IC50 values of 0.13 microM, 0.09 microM and 2.75 microM for AKT1, AKT2 and AKT3, respectively. Engasertib inhibits AKT phosphorylation and modulates downstream signalling in vitro. Engasertib can inhibit cancer cell proliferation and tumor growth[1].
  • SMILES
    O=C1N(CC)C2=CC(C3=CC=CC=C3)=C(C4=CC=C([C@@]5(N)C[C@H](O)C5)C=C4)N=C2OC1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200