Eniluracil

MedChem Express

Eniluracil [59989-18-3]

5

59989-18-3

Research Use Only

99.93

C6H4N2O2

136.11

Eniluracil (5-Ethynyluracil) is an orally active dihydropyrimidine dehydrogenase ( DPD ) inhibitor. Eniluracil irreversibly inhibits DPD , increases the oral bioavailability of 5-fluorouracil to 100%, and facilitates the uniform absorption and toxicity of 5-fluorouracil. Eniluracil can be used in cancer research of combination with fluoropyrimidines (including 5-fluorouracil) [1] [2] . Eniluracil is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(N1)NC=C(C#C)C1=O

-20°C,2°C to 8°C

12352200