Enniatin B1 [19914-20-6]

AdipoGen Life Sciences

Enniatin B1

10

19914-20-6

Research Use Only

>96%

Warning

C34H59N3O9

653.9

Chemical. CAS: 19914-20-6. Formula: C34H59N3O9. MW: 653.9. Isolated from fungus Fusarium sp. Cyclohexadepsipeptide mycotoxin. One of four major analogs in the enniatin complex. Commonly found food contaminant in cereals and their products. Ionophore antibiotic. Incorporation into the cell membrane forms dimeric structures that transport monovalent ions across the membrane (especially the mitochondrial membranes) affecting oxidative phosphorylation uncoupling. Anticancer compound. Triggers apoptosis in several cancer cell lines, decreasing the activation of the cell proliferation kinase, ERK (p44/p42). Moderate inhibitor of ACAT (acylcoenzyme A:cholesterolacyl transferase). Inhibitor of the pleiotropic drug resistance protein 5 (Pdr5p) in yeast. Shown to have a variety of other biological activities such as antifungal, anthelmintic, insecticidal, immunomodulatory and phytotoxic activity. - Cyclohexadepsipeptide mycotoxin. One of four major analogs in the enniatin complex. Commonly found food contaminant in cereals and their products. Ionophore antibiotic. Incorporation into the cell membrane forms dimeric structures that transport monovalent ions across the membrane (especially the mitochondrial membranes) affecting oxidative phosphorylation uncoupling. Anticancer compound. Triggers apoptosis in several cancer cell lines, decreasing the activation of the cell proliferation kinase, ERK (p44/p42). Moderate inhibitor of ACAT (acylcoenzyme A:cholesterolacyl transferase). Inhibitor of the pleiotropic drug resistance protein 5 (Pdr5p) in yeast. Shown to have a variety of other biological activities such as antifungal, anthelmintic, insecticidal, immunomodulatory and phytotoxic activity.

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-20°C,2°C to 8°C

12352200