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Ensartinib hydrochloride [2137030-98-7]

Ensartinib hydrochloride [2137030-98-7]

T22324
TargetMol Chemicals
CAS Number2137030-98-7
Product group Chemicals
Estimated Purity99.29%
Molecular Weight634.36
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Ensartinib hydrochloride
  • Delivery Days Customer
    4
  • CAS Number
    2137030-98-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Ensartinib hydrochloride
  • Estimated Purity
    99.29%
  • Molecular Formula
    C26H29Cl4FN6O3
  • Molecular Weight
    634.36
  • Scientific Description
    Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L1196M, S1206R, and T1151 mutants) with in vitro IC50s of <4 nM.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Cl.C[C@@H](Oc1cc(nnc1N)C(=O)Nc1ccc(cc1)C(=O)N1C[C@H](C)N[C@H](C)C1)c1c(Cl)ccc(F)c1Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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