ent-Avibactam (sodium) [396731-20-7]

MedChem Express

ent-Avibactam (sodium) [396731-20-7]

9

396731-20-7

Research Use Only

C7H10N3NaO6S

287.23

ent-Avibactam sodium (AVE1330A) is a new beta-lactamase inhibitor with broad-spectrum antibacterial activity. ent-Avibactam sodium, in combination with ceftazidime, exhibits significant inhibitory effects on Enterobacteriaceae that produce Ambler class A and class C beta-lactamases. The IC50 value of ent-Avibactam sodium is much lower than the commonly used beta-lactamase inhibitors clavulanic acid and ticarbonitrile, showing its ability to inhibit TEM-1 and P99 enzyme efficiency[1].

NC([C@@H]1[N@]2C(N([C@@H](CC1)C2)OS(=O)(O[Na])=O)=O)=O

12131703