ENTPD5 Antibody

Cusabio

ENTPD5 Antibody

20

ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

ENTPD5

ectonucleoside triphosphate diphosphohydrolase 5 (inactive)

CD39L4, NTPDase-5, PCPH, nucleoside diphosphate phosphatase ENTPD5, CD39 antigen-like 4, CD39-like 4, ER-UDPase, GDPase ENTPD5, NTPDase 5, Pcph proto-oncogene protein, UDPase ENTPD5, guanosine-diphosphatase ENTPD5, inosine diphosphate phosphatase ENTPD5, nucleoside diphosphatase, proto-oncogene CPH, uridine-diphosphatase ENTPD5

Rabbit

IgG

Nucleoside diphosphate phosphatase ENTPD5

Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.

Human, Mouse

-20°C or -80°C

41116161