Entrectinib [1108743-60-7]
HY-12678
CAS Number1108743-60-7
Product group Chemicals
Estimated Purity99.87
Molecular Weight560.64
Overview
- SupplierMedChem Express
- Product NameEntrectinib [1108743-60-7]
- Delivery Days Customer9
- CAS Number1108743-60-7
- CertificationResearch Use Only
- Estimated Purity99.87
- Molecular FormulaC31H34F2N6O2
- Molecular Weight560.64
- Scientific DescriptionEntrectinib (NMS-E628) is an orally active, BBB-penetrated and centrally active inhibitor of TrkA/B/C, ROS1 and ALK, with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Entrectinib induces apoptosis and cycle arrest in cancer cells, has antitumor activity, and attenuates bleomycin-induced lung fibrosis in mice[1][2][3].
- SMILESO=C(NC1=NNC2=C1C=C(CC3=CC(F)=CC(F)=C3)C=C2)C4=C(NC5CCOCC5)C=C(N6CCN(C)CC6)C=C4
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number1108743-60-7
Estimated Purity99.61%
Molecular Weight560.64
- SizePrice
Product group Chemicals
CAS Number1108743-60-7
Molecular Weight560.64
- SizePrice
