EP3 antagonist 6

MedChem Express

EP3 antagonist 6

14

Research Use Only

C31H37NO4

487.63

EP3 antagonist 6 (compound 5) is a potent, orally and selective EP3 receptor antagonist, with an IC50 of 1.9 nM. EP3 antagonist 6 can inhibits PGE2-induced (HY-101952) uterine contraction in pregnant rats[1].

CC(C)C[C@H](C1=CC(C)=CC(C)=C1)NC(C2=C(C=CC(COC3=C(C=CC=C3)C)=C2)CCC(O)=O)=O

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