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Epertinib (hydrochloride)

HY-107367A
MedChem Express
CAS Number2071195-74-7
Product group Chemicals
Estimated Purity98.25
Molecular Weight596.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Epertinib (hydrochloride) [2071195-74-7]
  • Delivery Days Customer
    10
  • CAS Number
    2071195-74-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.25
  • Molecular Formula
    C30H28Cl2FN5O3
  • Molecular Weight
    596.48
  • Scientific Description
    Epertinib (S-22611) hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR , HER4 and HER2 , with IC 50 s of 1.48 nM, 2.49 nM and 7.15 nM, respectively. Epertinib hydrochloride shows potent antitumor activity [1] [2] . Epertinib (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • SMILES
    CC#C/C(C1=CC2=C(NC3=CC=C(OCC4=CC=CC(F)=C4)C(Cl)=C3)N=CN=C2C=C1)=N\OC[C@@H]5NCCOC5.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200