EphB2 blocking peptide
GTX89205-PEP
Product group Proteins / Signaling Molecules
Overview
- SupplierGeneTex
- Product NameEphB2 blocking peptide
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352202