EPI-001 [227947-06-0]

MedChem Express

EPI-001 [227947-06-0]

9

227947-06-0

Research Use Only

99.34

C21H27ClO5

394.89

EPI-001, a selective inhibitor of Androgen Receptor (AR), targets transactivation unit 5 (Tau-5) of the AR. EPI-001 can inhibit transactivation of the AR amino-terminal domain (NTD), with an IC50 of ~6 microM. EPI-001 is also a selective modulator of PPARgamma. EPI-001 is active against castration-resistant prostate cancer[1][2][3].

OCC(O)COC1=CC=C(C(C)(C2=CC=C(OCC(O)CCl)C=C2)C)C=C1

-20°C,2°C to 8°C

12352200