Epinastine (hydrochloride) [108929-04-0]

MedChem Express

Epinastine (hydrochloride) [108929-04-0]

9

108929-04-0

Research Use Only

99.73

C16H16ClN3

285.77

Epinastine hydrochloride (WAL801 hydrochloride) is a selective and orally active histamine H1 receptor antagonist, CD96/PVR inhibitor and mast cell stabilizer. Epinastine hydrochloride has high affinity for neuronal octopamine receptors in locusts (Ki = 2 nM) and honeybees (Ki = 1.1 nM). Epinastine hydrochloride inhibits TARC, IL-8, and IL-4. Epinastine hydrochloride activates anti-colon cancer immunity and inhibits Substance P (HY-P0201)-induced scratching behavior and increased vascular permeability. Epinastine hydrochloride can be used in the research of allergic diseases[1][2][3][4][5][6][7][8].

NC1=NCC2N1C3=CC=CC=C3CC4=CC=CC=C24.[H]Cl

2°C to 8°C

12352200