Eplivanserin [130579-75-8]

MedChem Express

Eplivanserin [130579-75-8]

10

130579-75-8

Research Use Only

C19H21FN2O2

328.39

Eplivanserin (SR-46349) is a potent, selective and orally active 5-HT2A receptor antagonist, with an IC50 of 5.8 nM in rat cortical membrane, and a Kd of 1.14 nM. Eplivanserin displays >20-fold selectivity more selective for 5-HT2A than 5-HT2B and 5-HT2C[1][2].

OC1=CC=C(/C=C/C(C2=CC=CC=C2F)=N/OCCN(C)C)C=C1

12352200