EPOR-CD131 Heterodimer, Human (HEK293, Fc)

MedChem Express

EPOR-CD131 Heterodimer, Human (HEK293, Fc)

10

Research Use Only

96.00

CSF2RB

colony stimulating factor 2 receptor subunit beta

beta common cytokine receptor; beta-GM-CSF receptor; betaGMR; CD131; CDw131; colony stimulating factor 2 receptor beta common subunit; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); colony-stimulating factor-2 receptor, beta, low-affinity; cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL3RB; IL5RB; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); SMDP5

Erythropoietin receptor

The EPOR Protein functions as a receptor for erythropoietin, mediating erythroblast proliferation and differentiation upon EPO stimulation. The heterodimer triggers the JAK2/STAT5 signaling cascade and, in certain cell types, activates STAT1, STAT3, and the LYN tyrosine kinase. Additionally, isoform EPOR-T acts as a dominant-negative receptor, modulating EPOR-mediated signaling pathways. EPOR-CD131 Heterodimer Protein, Human (HEK293, Fc) is a recombinant protein dimer complex containing human-derived EPOR-CD131 Heterodimer protein, expressed by HEK293 , with C-hFc labeled tag. EPOR-CD131 Heterodimer Protein, Human (HEK293, Fc), has molecular weight of ~110-130 kDa.

-20°C

41116100