Epothilone B

MedChem Express

Epothilone B [152044-54-7]

10

152044-54-7

Research Use Only

99.91

C27H41NO6S

507.68

Epothilone B is a microtubule stabilizer with a K i of 0.71microM. It acts by binding to the alphabeta-tubulin heterodimer subunit which causes decreasing of alphabeta-tubulin dissociation.

O=C(C[C@H](O)C1(C)C)O[C@H](/C(C)=C/C2=CSC(C)=N2)C[C@]3([H])O[C@]3(C)CCC[C@H](C)[C@H](O)[C@@H](C)C1=O

-20°C

12352200