Equine TGF Beta 2 ELISA Kit

Arigo Biolaboratories

Equine TGF Beta 2 ELISA Kit

23

ELISA

31.2 pg/ml - 2,000 pg/ml

Intra-Assay CV: 5.6%Inter-Assay CV: 6.2%

15 pg/ml

~ 5 hours

Research Use Only

HRP

Transforming growth factor beta-2 proprotein

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]

2°C to 8°C

41116100

Human, Mouse