ER 50891 [187400-85-7]
HY-108531
CAS Number187400-85-7
Product group Chemicals
Estimated Purity99.86
Molecular Weight432.51
Overview
- SupplierMedChem Express
- Product NameER 50891 [187400-85-7]
- Delivery Days Customer5
- CAS Number187400-85-7
- CertificationResearch Use Only
- Estimated Purity99.86
- Molecular FormulaC29H24N2O2
- Molecular Weight432.51
- Scientific DescriptionER 50891 is a RARalpha antagonist. ER 50891 can significantly antagonize the inhibitory effect of all-trans retinoic acid (ATRA) on the total cell metabolic activity and proliferation of MC3T3-E1 preosteoblasts. ER 50891 rescues ATRA-inhibited osteocalcin (OCN) expression and extracellular matrix mineralization, and suppresses alkaline phosphatase (ALP) activity synergistically. ER 50891 can be used for the study of osteoporosis related to ATRA-induced inhibition of osteoblastogenesis[1].
- SMILESO=C(O)C1=CC=C(C2=CC=C(C3=NC4=C(C(C)C)C=CC=C4C(C5=CC=CC=C5)=C3)N2)C=C1
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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