Eragidomide

MedChem Express

Eragidomide [1860875-51-9]

9

1860875-51-9

Research Use Only

99.86

C22H18ClF2N3O4

461.85

Eragidomide (CC-90009) is a first-in-class GSPT1-selective cereblon (CRBN) E3 ligase modulator, acts as a molecular glue. Eragidomide coopts the CRL4 CRBN to selectively target GSPT1 for ubiquitination and proteasomal degradation [1] [2] .

O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)C(F)(F)C4=CC=C(Cl)C=C4

-20°C,2°C to 8°C

12352200