ERBB3 / HER3 Antibody (clone M908, Preservative Free)

LifeSpan BioSciences

ERBB3 / HER3 Antibody (clone M908, Preservative Free)

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Block: In a functional ELISA which immobilized recombinant Human NRG1/Fc Chimera at 5 ug/ml (100 microL/well) in the plate, the Mouse Anti-Human ErBB3 Monoclonal Antibody can block the binding of 1 ug/ml of biotinylated Human ErBB3 to Human NRG1/Fc Chimera, the EC50 is 1.30 ug/ml. Neutralization: The neutralization activity of Erbb3 neutralizing antibody is Measured by its ability to neutralize NRG1-beta1/HRG1-beta1-induced proliferation in the MCF-7 human breast cancer cell line. Please Note: Optimal concentrations/dilutions should be determined by the end user.. Block (1 µg/ml), ELISA (5 µg/ml), Neut Block: In a functional ELISA which immobilized recombinant Human NRG1/Fc Chimera at 5 ug/ml (100 µL/well) in the plate, the Mouse Anti-Human ErBB3 Monoclonal Antibody can block the binding of 1 ug/ml of biotinylated Human ErBB3 to Human NRG1/Fc Chimera, the EC50 is 1.30 ug/ml. Neutralization: The neutralization activity of Erbb3 neutralizing antibody is Measured by its ability to neutralize NRG1­ß1/HRG1­ß1­induced proliferation in the MCF­7 human breast cancer cell line. Please Note: Optimal concentrations/dilutions should be determined by the end user.

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

M908

Unconjugated

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ERBB3

erb-b2 receptor tyrosine kinase 3

ErbB-3, FERLK, HER3, LCCS2, MDA-BF-1, VSCN1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3, receptor tyrosine-protein kinase erbB-3, human epidermal growth factor receptor 3, proto-oncogene-like protein c-ErbB-3, tyrosine kinase-type cell surface receptor HER3, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

Mouse

IgG1

-20°C or -80°C,2°C to 8°C

12352203