ERBB3 / HER3 Antibody (clone mh908, Preservative Free)

LifeSpan BioSciences

ERBB3 / HER3 Antibody (clone mh908, Preservative Free)

14

Block: In a functional ELISA which immobilized recombinant Human NRG1/Fc Chimera at 5 ug/ml (100 microL/well) in the plate, tthe Mouse and Human Chimeric anti-Human ErBB3 Monoclonal Antibody can block the binding of 1 ug/ml of biotinylated Human ErBB3 to Human NRG1/Fc Chimera, the EC50 is 2. 62 ug/ml. Neutralization: The neutralization activity of Erbb3 Neutralizing Antibody is Measured by its ability to neutralize NRG1-beta1/HRG1-beta1 induced proliferation in the MCF-7 human breast cancer cell line. The Neutralization titer (IC50) is typically 15-75 ng/mL in the presence of 40 ng/mL Recombinant Human NRG1-beta1/HRG1-beta1. Please Note: Optimal concentrations/dilutions should be determined by the end user.. Block (1 µg/ml), ELISA (5 µg/ml), Neut (40 ng/ml) Block: In a functional ELISA which immobilized recombinant Human NRG1/Fc Chimera at 5 ug/ml (100 µL/well) in the plate, tthe Mouse and Human Chimeric anti-Human ErBB3 Monoclonal Antibody can block the binding of 1 ug/ml of biotinylated Human ErBB3 to Human NRG1/Fc Chimera, the EC50 is 2. 62 ug/ml. Neutralization: The neutralization activity of Erbb3 Neutralizing Antibody is Measured by its ability to neutralize NRG1-ß1/HRG1-ß1 induced proliferation in the MCF-7 human breast cancer cell line. The Neutralization titer (IC50) is typically 15-75 ng/mL in the presence of 40 ng/mL Recombinant Human NRG1-ß1/HRG1-ß1. Please Note: Optimal concentrations/dilutions should be determined by the end user.

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

mh908

Unconjugated

...

ERBB3

erb-b2 receptor tyrosine kinase 3

ErbB-3, FERLK, HER3, LCCS2, MDA-BF-1, VSCN1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3, receptor tyrosine-protein kinase erbB-3, human epidermal growth factor receptor 3, proto-oncogene-like protein c-ErbB-3, tyrosine kinase-type cell surface receptor HER3, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

Mouse

IgG1

-20°C or -80°C,2°C to 8°C

12352203