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ERCC8 antibody

GTX100122
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetERCC8
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Overview

  • Supplier
    GeneTex
  • Product Name
    ERCC8 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    5.39 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1161
  • Target name
    ERCC8
  • Target description
    ERCC excision repair 8, CSA ubiquitin ligase complex subunit
  • Target synonyms
    CKN1; cockayne syndrome WD repeat protein CSA; Cockayne syndrome WD-repeat protein CSA; CSA; DNA excision repair protein ERCC-8; excision repair cross-complementation group 8; excision repair cross-complementing rodent repair deficiency, complementation group 8; UVSS2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13216
  • Protein Name
    DNA excision repair protein ERCC-8
  • Scientific Description
    This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Heat shock protein DNAJA2 regulates transcription-coupled repair by triggering CSB degradation via chaperone-mediated autophagy.
    Read more