ERCC8 antibody
GTX100122
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetERCC8
Overview
- SupplierGeneTex
- Product NameERCC8 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration5.39 mg/ml
- ConjugateUnconjugated
- Gene ID1161
- Target nameERCC8
- Target descriptionERCC excision repair 8, CSA ubiquitin ligase complex subunit
- Target synonymsCKN1; cockayne syndrome WD repeat protein CSA; Cockayne syndrome WD-repeat protein CSA; CSA; DNA excision repair protein ERCC-8; excision repair cross-complementation group 8; excision repair cross-complementing rodent repair deficiency, complementation group 8; UVSS2
- HostRabbit
- IsotypeIgG
- Protein IDQ13216
- Protein NameDNA excision repair protein ERCC-8
- Scientific DescriptionThis gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Heat shock protein DNAJA2 regulates transcription-coupled repair by triggering CSB degradation via chaperone-mediated autophagy.Read more