Western Blot analysis of 1) Hela, 2)Mouse brain, 3) Rat brain using ERK 1/2 Monoclonal Antibody at dilution of 1:2000.
ERK 1/2 Monoclonal Antibody
![Research Use Only](static/images/certificates/ruo.jpg)
E-AB-22142
Product group Antibodies
Overview
- SupplierElabscience
- Product NameERK 1/2 Monoclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionInvolved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
- UNSPSC12352203