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ERK2 antibody [N2C3]

Research Use Only
GTX113094
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Feline, Human, Mouse, Porcine, Rat
TargetMAPK1
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    ERK2 antibody [N2C3]
  • Delivery Days Customer
    9
  • Antibody Specificity
    IP/MS validation was supported by references (PMID:30377410)
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5594
  • Target name
    MAPK1
  • Target description
    mitogen-activated protein kinase 1
  • Target synonyms
    ERK; ERK2; ERK-2; ERT1; extracellular signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAPK 2; MAPK2; mitogen-activated protein kinase 1; mitogen-activated protein kinase 2; NS13; p38; p40; p41; p41mapk; P42MAPK; p42-MAPK; PRKM1; PRKM2; protein tyrosine kinase ERK2
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq]
  • Reactivity
    Canine, Feline, Human, Mouse, Porcine, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • PM2.5 facilitates IL-6 production in human osteoarthritis synovial fibroblasts via ASK1 activation. Liu JF et al., 2021 Mar, J Cell Physiol
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  • The alpha9 Nicotinic Acetylcholine Receptor Mediates Nicotine-Induced PD-L1 Expression and Regulates Melanoma Cell Proliferation and Migration. Nguyen HD et al., 2019 Dec 11, Cancers (Basel)
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  • Loss of endosomal recycling factor RAB11 coupled with complex regulation of MAPK/ERK/AKT signaling in postmortem spinal cord specimens of sporadic amyotrophic lateral sclerosis patients. Mitra J et al., 2019 Jun 13, Mol Brain
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  • Novel Role for miR-1290 in Host Species Specificity of Influenza A Virus. Huang SY et al., 2019 Sep 6, Mol Ther Nucleic Acids
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  • A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat Methods
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  • Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers. Nana AW et al., 2018 Oct, Horm Cancer
    Read more
  • 18beta-glycyrrhetinic acid inhibits migration and invasion of human gastric cancer cells via the ROS/PKC-alpha/ERK pathway. Cai H et al., 2018 Jan, J Nat Med
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  • 2,3,5,4-Tetrahydroxystilbene-2-O-beta-glucoside Isolated from Polygoni Multiflori Ameliorates the Development of Periodontitis. Chin YT et al., 2016, Mediators Inflamm
    Read more
  • Actions of l-thyroxine and Nano-diamino-tetrac (Nanotetrac) on PD-L1 in cancer cells. Lin HY et al., 2016 Oct, Steroids
    Read more
  • The protective effects of spirulina in cyclophosphamide induced nephrotoxicity and urotoxicity in rats. Sinanoglu O et al., 2012 Dec, Urology
    Read more