ERK5-IN-4 [1888305-17-6]

MedChem Express

ERK5-IN-4 [1888305-17-6]

10

1888305-17-6

Research Use Only

C16H11Cl2FN4O2

381.19

ERK5-IN-4 (compound 34b) is a potent and selective inhibitor of extracellular signal-related kinase 5 (ERK5). ERK5-IN-4 inhibits ERK5 (full-length) and truncated ERK5 (ERK5 deltaTAD) kinase activity in HEK293 cells with an IC50 of 77 nM and 300 nM, respectively[1].

O=C(C1=CC(C(C2=C(Cl)C=CC(Cl)=C2F)=O)=CN1)NC3=CN(C)N=C3

12131703