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Erlotinib hydrochloride [183319-69-9]

Research Use Only
SYN-1039
SYNkinase
CAS Number183319-69-9
Product group Chemicals
Estimated Purity>95%
Molecular Weight393.4 . 36.5
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Overview

  • Supplier
    SYNkinase
  • Product Name
    Erlotinib hydrochloride [183319-69-9]
  • Delivery Days Customer
    10
  • CAS Number
    183319-69-9
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Danger
  • Molecular Formula
    C22H23N3O4 . HCl
  • Molecular Weight
    393.4 . 36.5
  • Scientific Description
    Chemical. CAS: 183319-69-9. Formula: C22H23N3O4 . HCl. MW: 393.4 . 36.5. Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC(50) of 2nM against EGFR. It is >1000-fold more sensitive for EGFR than for c-Src or v-Abl. - Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC(50) of 2nM against EGFR. It is >1000-fold more sensitive for EGFR than for c-Src or v-Abl.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    51202000