Erlotinib hydrochloride [183319-69-9]
SYN-1039
CAS Number183319-69-9
Product group Chemicals
Estimated Purity>95%
Molecular Weight393.4 . 36.5
Overview
- SupplierSYNkinase
- Product NameErlotinib hydrochloride [183319-69-9]
- Delivery Days Customer10
- CAS Number183319-69-9
- CertificationResearch Use Only
- Estimated Purity>95%
- Hazard InformationDanger
- Molecular FormulaC22H23N3O4 . HCl
- Molecular Weight393.4 . 36.5
- Scientific DescriptionChemical. CAS: 183319-69-9. Formula: C22H23N3O4 . HCl. MW: 393.4 . 36.5. Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC(50) of 2nM against EGFR. It is >1000-fold more sensitive for EGFR than for c-Src or v-Abl. - Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC(50) of 2nM against EGFR. It is >1000-fold more sensitive for EGFR than for c-Src or v-Abl.
- Storage Instruction2°C to 8°C
- UNSPSC51202000