
Western blot All lanes: ERO1L antibody at 2.01ug/ml Lane 1: HepG2 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 54 kDa Observed band size: 54, 62 kDa
ERO1A Antibody
CSB-PA846631ESR1HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetERO1A
Overview
- SupplierCusabio
- Product NameERO1A Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID30001
- Target nameERO1A
- Target descriptionendoplasmic reticulum oxidoreductase 1 alpha
- Target synonymsendoplasmic oxidoreductin-1-like protein; endoplasmic reticulum oxidoreductase alpha; Ero1alpha; ERO1-alpha; ERO1L; ERO1-L; ERO1LA; ERO1-L-alpha; ERO1-like protein alpha; oxidoreductin-1-L-alpha
- HostRabbit
- IsotypeIgG
- Protein IDQ96HE7
- Protein NameERO1-like protein alpha
- Scientific DescriptionOxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203