ERP27, Human (HEK293, His)

MedChem Express

ERP27, Human (HEK293, His)

10

Research Use Only

ERP27

endoplasmic reticulum protein 27

C12orf46, PDIA8, endoplasmic reticulum resident protein 27, ER protein 27, endoplasmic reticulum protein 27 kDa, inactive protein disulfide-isomerase 27, protein disulfide isomerase family A, member 8

Endoplasmic reticulum resident protein 27

The ERP27 protein has a unique role in that it can specifically bind unfolded proteins and recruit the protein disulfide isomerase PDIA3 to the substrate through the hydrophobic pocket in its C-terminal domain. This interaction implies that ERP27 is involved in the unfolding stress response and resolves challenges in cellular proteostasis. ERP27 Protein, Human (HEK293, His) is the recombinant human-derived ERP27 protein, expressed by HEK293 , with C-6*His labeled tag.

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