ERP27, Human (HEK293, His)

MedChem Express

ERP27, Human (HEK293, His)

10

Research Use Only

ERP27

endoplasmic reticulum protein 27

C12orf46; endoplasmic reticulum protein 27 kDa; endoplasmic reticulum resident protein 27; ER protein 27; inactive protein disulfide-isomerase 27; PDIA8; protein disulfide isomerase family A, member 8

Endoplasmic reticulum resident protein 27

The ERP27 protein has a unique role in that it can specifically bind unfolded proteins and recruit the protein disulfide isomerase PDIA3 to the substrate through the hydrophobic pocket in its C-terminal domain. This interaction implies that ERP27 is involved in the unfolding stress response and resolves challenges in cellular proteostasis. ERP27 Protein, Human (HEK293, His) is the recombinant human-derived ERP27 protein, expressed by HEK293 , with C-6*His labeled tag.

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